Leukaemia breakthrough as genetic test predicts likelihood of developing common type of blood cancer

Scientists from eight UK universities and the Institute for Cancer Research have developed a genetic test to predict whether someone will develop a common type of leukaemia, a breakthrough which could lead to potential patients being warned about the risk of progressive Chronic Lymphocytic Leukaemia (CLL) and boost their chances of survival.

CLL affects white blood cells and usually develops over a long period and over many years, mostly affecting those aged over 60. It varies in severity, with some patients developing lumps in their necks and armpits, and weight loss, whole others display no symptoms.

Through the study of blood samples of people with CLL, researchers found they commonly had the same ‘genetic’ tendency’ to develop progress forms of the disease.

Dr David Allsup, haematology consultant, said “Not only does the research inform us if patients have the genetic tendency to develop progressive CLL, but it also enables us to determine whether or not a patient’s CLL will require treatment in the future or not.

“That way, we are able to keep a close eye on the patients with a high risk, and have treatment options available as soon as they are required.”

Professor James Allen of Newcastle University’s Centre for Cancer, said “Emerging evidence suggests that early treatment for patients at high risk of developing progressive CLL could significantly delay the onset of symptomatic leukaemia and improve survival.

“The results from this collaborative study will help patients and their doctors make important decisions about when to start treatment.”

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Posted by Karen Motley, Clinical Negligence Department, Chadwick Lawrence LLP (tonymay@chadlaw.co.uk ), medical negligence lawyers and clinical negligence solicitors in Huddersfield, Leeds, Wakefield and Halifax, West Yorkshire.

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